Related Experiment Video

Updated: Jan 21, 2026

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock
06:10

Utilizing Percutaneous Ventricular Assist Devices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

Published on: June 12, 2021

3.6K

Complete Versus Culprit only Revascularisation in Patients with Cardiogenic Shock Complicating Acute Myocardial

Krishnaraj S Rathod1, Sudheer Koganti1, Ajay K Jain1

  • 1Barts Health NHS Trust, London, United Kingdom of Great Britain and Northern Ireland.

Cardiovascular Revascularization Medicine : Including Molecular Interventions
|July 23, 2019
PubMed

Insights

Complete revascularisation in ST-segment myocardial infarction (STEMI) patients with cardiogenic shock (CS) and multi-vessel disease (MVD) is associated with reduced mortality. This approach appears more beneficial than treating only the culprit vessel.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Clinical Research

Background:

  • Cardiogenic shock (CS) in ST-segment myocardial infarction (STEMI) patients has high mortality rates.
  • Multi-vessel disease (MVD) is common in these patients, but optimal treatment remains unclear.

Purpose of the Study:

  • To assess management trends for CS patients with MVD.
  • To compare outcomes of complete revascularisation versus culprit-only revascularisation in STEMI patients with CS and MVD.

Main Methods:

  • Observational cohort study of 1058 STEMI patients with CS and MVD from 2005-2015.
  • Prospective data collection from British Cardiac Intervention Society (BCIS) PCI dataset.
  • Follow-up for a median of 4.1 years, analyzing all-cause mortality.

Main Results:

  • Complete revascularisation was performed in 47.0% of patients, with stable rates over time.
  • Crude in-hospital MACE rates were similar, but Kaplan-Meier analysis showed no significant difference in mortality.
  • Multivariate Cox analysis and propensity matching revealed complete revascularisation was associated with reduced mortality (HR 0.69 and 0.81, respectively).

Conclusions:

  • Complete revascularisation in STEMI patients with CS and MVD is associated with improved outcomes compared to culprit-vessel-only intervention.
  • Findings support ongoing clinical trials and provide evidence for complete revascularisation in STEMI.
  • This strategy may improve survival rates in high-risk cardiac patients.
Abstract

Keywords:
Cardiogenic shockMulti-vessel interventionMyocardial infarctionPrimary PCI

More Related Videos

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction14:19

Primary Outcome Assessment in a Pig Model of Acute Myocardial Infarction

Published on: October 14, 2016

12.0K
Myocardial Infarction and Functional Outcome Assessment in Pigs12:03

Myocardial Infarction and Functional Outcome Assessment in Pigs

Published on: April 25, 2014

28.6K

Related Concept Videos

Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.6K
Acid Attack on Concrete01:21

Acid Attack on Concrete

When acids come into contact with concrete, they initiate a chemical reaction that dissolves the hydrated cement paste. This process leads to softening and structural weakening of the concrete. This issue is commonly observed in environments such as chimneys, sewers, and industrial settings. The severity of the damage increases as the pH of the water interacting with the concrete drops below 6.5. In particular, a pH under 4.5 can cause significant concrete damage.
The rate at which hydrogen...
712
Sulfate Attack on Concrete01:29

Sulfate Attack on Concrete

Sulfate attack on concrete is a deterioration process characterized by a whitish discoloration beginning at the edges and corners, accompanied by cracking and spalling. This phenomenon occurs when sulfates react with the components of hardened concrete, forming compounds like calcium sulfate and calcium sulfoaluminate which occupy more space than the substances they replace, causing the concrete to expand and disrupt.
Sulfates from sources like soil, groundwater, or industrial effluents...
708
Shock Waves01:16

Shock Waves

While deriving the Doppler formula for the observed frequency of a sound wave, it is assumed that the speed of sound in the medium is greater than the source's speed through it. When this condition is breached, a shock wave occurs.
When the source's speed approaches the speed of sound, constructive interference between successive wavefronts emitted by the source occurs immediately behind it. Initially, scientists believed that this constructive interference would result in such high...
2.5K
Types of Reports II: Incident or Occurrence Report01:21

Types of Reports II: Incident or Occurrence Report

An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.2K
Hemodialysis II: Procedure and Complications01:24

Hemodialysis II: Procedure and Complications

DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
696