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Band Theory02:35

Band Theory

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When two or more atoms come together to form a molecule, their atomic orbitals combine and molecular orbitals of distinct energies result. In a solid, there are a large number of atoms, and therefore a large number of atomic orbitals that may be combined into molecular orbitals. These groups of molecular orbitals are so closely placed together to form continuous regions of energies, known as the bands.
The energy difference between these bands is known as the band gap.
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Isolated atoms have discrete energy levels that are well described by the Bohr model. And, it quantifies the energy of an electron in a hydrogen atom as En. Higher quantum numbers 'n' yield less negative, closer electron energy levels.
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As the human population continues to grow and use resources, we must be mindful of our planet’s natural limits. Sustainable development provides a pathway to maintain and improve human life now while also ensuring that future generations will have the resources that they need. The long-term success of sustainability efforts rests on understanding the interplay between human actions and ecological systems.
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Band keratopathy developing after denosumab injections.

Michael Trong Duc Nguyen1, Mikael Sebag1, Mona Harissi-Dagher1

  • 1Département d'ophtalmologie, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.

Digital Journal of Ophthalmology : DJO
|July 23, 2019
PubMed
Summary

Denosumab therapy for osteoporosis may cause band keratopathy, a corneal condition. This case highlights a potential adverse drug reaction affecting vision, necessitating prompt discontinuation and treatment.

Area of Science:

  • Ophthalmology
  • Pharmacology
  • Bone Metabolism

Background:

  • Denosumab is a monoclonal antibody used to treat osteoporosis by inhibiting bone resorption.

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  • Ocular adverse drug reactions to denosumab are rare, with limited documented cases.
  • Band keratopathy involves calcium deposits in the cornea, potentially impairing vision.