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Updated: Jan 21, 2026

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Cell Labeling and Injection in Developing Embryonic Mouse Hearts
Published on: April 17, 2014
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Band keratopathy developing after denosumab injections.
Michael Trong Duc Nguyen1, Mikael Sebag1, Mona Harissi-Dagher1
1Département d'ophtalmologie, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Digital Journal of Ophthalmology : DJO
|July 23, 2019
Summary
Denosumab therapy for osteoporosis may cause band keratopathy, a corneal condition. This case highlights a potential adverse drug reaction affecting vision, necessitating prompt discontinuation and treatment.
Area of Science:
- Ophthalmology
- Pharmacology
- Bone Metabolism
Background:
- Denosumab is a monoclonal antibody used to treat osteoporosis by inhibiting bone resorption.
- Ocular adverse drug reactions to denosumab are rare, with limited documented cases.
- Band keratopathy involves calcium deposits in the cornea, potentially impairing vision.
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