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A Case Report of Seronegative Limbic Encephalitis
Maham Munawar1, Pulwasha M Iftikhar2, Jehanzeb A Khan3
1Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
Autoimmune encephalitis, including limbic encephalitis (LE), often lacks clear symptoms, complicating diagnosis. This case highlights the diagnostic challenges of seronegative LE in a young patient presenting with cognitive decline and seizures.
Area of Science:
- Neurology
- Immunology
- Neuroscience
Background:
- Autoimmune encephalitis encompasses a spectrum of neurological disorders characterized by inflammation of the brain.
- Limbic encephalitis (LE), a subtype, specifically affects the limbic system, leading to acute neurological deficits.
- Diagnosis relies heavily on identifying specific autoimmune antibodies, but seronegative cases present diagnostic challenges.
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