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Three new pterocarpans from the aerial parts of Abrus Precatorius
Yan Li1,2, Jie-Wei Wu1,3, Hai-Bo Tan1
1Program for Natural Products Medicinal Chemistry, Key Laboratory of Plant Resources Conservation and Sustainable Utilization, Guangdong Provincial Key Laboratory of Applied Botany, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, China.
Abstract:
Three new pterocarpans, named abrusprecatins A-C (1-3), along with three known ones, namely medicarpin (4), maackiain (5), and 4-hydroxy-3-methoxy-8,9-methylenedioxypterocarpan (6) were isolated from the aerial parts of Abrus precatorius. The structures of these compounds were established by extensive analysis of mass spectrometric data, 1 D and 2 D NMR spectroscopic data. In addition, the absolute configurations were determined by a combination of single crystal X-ray diffraction analysis and circular dichroism spectroscopy.
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