Related Experiment Video
Updated: Jan 21, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents HPHC
Published on: May 10, 2016
Phenolic constituents from the fresh pericarps of Juglans sigillata
Yi Lin1, Jingjing Liang1, Xiaogang Peng1
1School of Pharmacy, Tongji Medical College of Huazhong University of Science and Technology, Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Wuhan, People's Republic of China.
Abstract:
Three new phenolic compounds, 2,3,4-trihydroxy-1-(4'-hydroxybenzyl)benzoic acid (1), 2,3,4-trihydroxy-1-(4'-hydroxy-3'-methoxybenzyl)benzoic acid (2), and 2-(4'-hydroxy-3'-methoxybenzyl)-3,5-dimethoxy-1,4-benzoquinone (3), were isolated from the fresh pericarps of Juglans sigillata Dode. Their structures were elucidated by integrated spectroscopic techniques. Bioactivity screening results showed that compounds 1-3 exhibited moderate neuroprotective effects against H2O2-induced or CoCl2-induced cellular damage in human neuroblastoma SH-SY5Y cell line.
More Related Videos
Related Concept Videos
Oxidation of Phenols to Quinones
o-hydroxy phenols are oxidized to o-quinones and p-hydroxy phenols to p-quinones. Such redox reactions involve the transfer of two electrons and two protons. The reversible redox...
Structure and Nomenclature of Alcohols and Phenols
Alcohols are one of the most important functional groups in organic chemistry. The name of alcohol comes from the hydrocarbon from which it is derived. Alcohols are organic molecules containing the functional hydroxyl or –OH group directly bonded to carbon. Phenols have an OH group directly attached to a benzene ring. While alcohols are colorless, phenol is a white crystalline compound with a characteristic "hospital smell" odor.
As with other organic compounds, alcohols and...
Physical Properties of Alcohols and Phenols
Alcohols possess a higher boiling point than aliphatic hydrocarbons of similar...
Acidity and Basicity of Alcohols and Phenols
Hydrolysis of Chlorobenzene to Phenol: Dow Process
Segregation in Fresh Concrete

