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The clinical varicocele in infertility
1Department of Surgery, Holy Family Hospital, Karachi, Pakistan.
British Journal of Urology
|April 1, 1988
Summary
Varicocele affects 20% of infertile males, often causing abnormal sperm counts and motility. Selective treatment, including surgery or medical therapy, can improve sperm parameters in these heterogeneous patients.
Area of Science:
- Urology
- Reproductive Medicine
- Andrology
Background:
- Varicocele is a common cause of male infertility.
- Understanding the heterogeneity of varicocele's impact on sperm parameters is crucial for effective treatment.
Purpose of the Study:
- To analyze the characteristics of infertile males with varicocele.
- To evaluate the effectiveness of different treatment modalities for varicocele-associated infertility.
Main Methods:
- Retrospective analysis of 238 infertile males over 47 months.
- Assessment of sperm parameters, hormonal levels (FSH, LH, prolactin, testosterone), and treatment outcomes.
- Comparison of outcomes following surgery, medical treatment, or combined approaches.
Main Results:
- 20% of infertile males had varicocele, with 51% abnormal sperm counts and 60% reduced motility.
- Hormonal abnormalities were frequent, with elevated FSH (48%) and LH (70%).
- Selective treatment, including surgery and medical therapies, led to improved sperm parameters and pregnancy in some cases.
Conclusions:
- Infertile patients with varicocele represent a heterogeneous group.
- Tailored treatment strategies, encompassing surgery, medical treatment, or a combination, are essential for optimizing spermiogram improvements.