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A Clinical Approach to Diagnosing Encephalopathy.
Michael G Erkkinen1, Aaron L Berkowitz1
1Department of Neurology, Brigham and Women's Hospital, Boston, Mass.
The American Journal of Medicine
|July 23, 2019
Summary
Encephalopathy is brain dysfunction affecting consciousness, stemming from various causes. This article focuses on diagnosing primary neurologic origins by categorizing them based on onset speed.
Area of Science:
- Neurology
- Neuroscience
- Internal Medicine
Background:
- Encephalopathy signifies brain dysfunction impacting consciousness.
- Causes range from primary neurological issues to systemic conditions.
- Accurate diagnosis is crucial for effective patient management.
Purpose of the Study:
- To outline a systematic approach for the differential diagnosis of encephalopathy.
- To emphasize primary neurologic causes of encephalopathy.
- To provide a practical framework for organizing diagnostic considerations.
Main Methods:
- Review of existing literature on encephalopathy.
- Discussion of diagnostic criteria and approaches.
- Categorization of etiologies based on temporal profile (onset and progression).
Main Results:
- Encephalopathy presents with altered consciousness due to brain dysfunction.
- Differential diagnosis includes a wide spectrum of primary neurologic and systemic disorders.
- A temporal classification (sudden, acute, subacute, chronic) aids in differential diagnosis.
Conclusions:
- A structured approach to diagnosing encephalopathy is essential.
- Focusing on primary neurologic causes requires systematic evaluation.
- Categorizing by onset speed offers a practical diagnostic schema.
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