Related Experiment Video
Updated: Jan 21, 2026
Handwriting Analysis Indicates Spontaneous Dyskinesias in Neuroleptic Naïve Adolescents at High Risk for Psychosis
Published on: November 21, 2013
Preoperative Risk Stratification of Adnexal Masses in the Pediatric and Adolescent Population: Evaluating the
Hanna R Goldberg1, Sari Kives2, Lisa Allen2
1Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Study Objective:
To evaluate the diagnostic performance of the Decision Tree System (DTS) rules 2 and 3 for surgically managed adnexal masses in the North American population and to compare it with the risk stratification criteria used at The Hospital for Sick Children (≥8 cm and complex/solid).
Design:
A retrospective cohort study of patients who presented with adnexal masses and were surgically treated between April 2011 and March 2016.
Setting:
The Hospital for Sick Children (Toronto, Ontario, Canada).
Participants:
Patients 1-18 years of age with adnexal masses who underwent surgical treatment.
Interventions And Main Outcome Measures:
Main outcome measures included diagnostic performance (preoperative sensitivity, specificity, positive predictive value [PPV], and negative predictive value [NPV] for malignancy) of the DTS rules 2 and 3 and ≥8 cm and complex/solid criteria.
Results:
The malignancy rate was 10.4%. The DTS rules 2 and 3 had a sensitivity of 84% (95% confidence interval [CI], 79-90), specificity of 77% (95% CI, 71-83), PPV of 30% (95% CI, 17-42), and NPV of 98% (95% CI, 94-100). The 8 cm or larger and complex/solid criteria had a sensitivity of 89% (95% CI, 85-94), specificity of 71% (95% CI, 64-77), PPV of 27% (95% CI, 16-38), and NPV of 98% (95% CI, 96-100).
Conclusion:
Our study showed that DTS rules 2 and 3 had similar diagnostic performance as the 8 cm or larger and complex/solid criteria in the same population, with a very high NPV and a low PPV. Future prospective investigations should be conducted to further assess how DTS components can be incorporated into future algorithms for the management of adnexal masses in the pediatric population.
More Related Videos
05:56Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
Published on: August 29, 2025
19:15Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale
Published on: August 25, 2014
Related Concept Videos
02:40The Tree of Life - Bacteria, Archaea, Eukaryotes
02:04Conservation of Small Populations
01:19Survival Tree
Building a Survival Tree
Constructing a...
01:18Cognitive Development During Adolescence
01:23The Bronchial Tree
The trachea, commonly known as the windpipe, is a tube that connects the larynx (voice box) to the bronchi. At a point called the carina, it bifurcates into two primary bronchi. The right primary bronchus is wider, shorter, and more vertical than the left primary...
03:21Phylogenetic Trees