Related Experiment Video
Updated: Jan 21, 2026
18:38
Large-scale Gene Knockdown in C. elegans Using dsRNA Feeding Libraries to Generate Robust Loss-of-function Phenotypes
Published on: September 25, 2013
12.4K
Fetal phenotypes emerge as genetic technologies become robust
Kathryn J Gray1, Louise E Wilkins-Haug1, Nancy J Herrig1
1Division of Maternal Fetal Medicine and Reproductive Genetics, Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, MA, USA.
Prenatal Diagnosis
|July 23, 2019
Summary
Detailed fetal phenotyping is crucial for interpreting prenatal genomic testing. Improved in utero assessments enhance genetic diagnosis and fetal development understanding.
Area of Science:
- Medical Genetics
- Fetal Medicine
- Genomics
Background:
- Prenatal genomic evaluation is increasingly accessible, yet fetal genotype-phenotype correlations are underdeveloped.
- Established genotype-phenotype databases exist for pediatric and adult populations, but a similar system for fetal genomics is lacking.
- Current fetal prognostic counseling is challenged by a lack of prenatal-specific outcome data.
Related Concept Videos
01:27Emerging Adulthood
640
Jeffrey Arnett's concept of emerging adulthood offers a framework to understand the unique developmental stage between adolescence and full-fledged adulthood, generally from ages 18 to 25. This period is marked by extensive exploration and shifts in identity, relationships, and career choices, a process known in psychology as role experimentation. Emerging adulthood reflects the evolving cultural expectations surrounding adulthood and the dynamic process of personal transformation during...
640
01:14Fetal Circulation
2.7K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
2.7K
01:30Introduction Cardiac Emergencies
300
Cardiac emergencies are critical situations involving the heart that require immediate medical intervention to prevent severe complications or death. These emergencies often arise from underlying heart conditions that impair the heart's ability to function correctly.Types of Cardiac EmergenciesThe most common types of cardiac emergencies include Acute Coronary Syndrome (ACS), myocardial infarction (MI), cardiac arrest, and heart failure.Acute Coronary Syndrome (ACS)Acute Coronary Syndrome (ACS)...
300
01:11Genetic Lingo
114.0K
Overview
114.0K
02:16Genetics of Speciation
20.9K
Speciation is the evolutionary process resulting in the formation of new, distinct species—groups of reproductively isolated populations.
20.9K
01:25What is Population Genetics?
64.5K
A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.5K