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Cardiovascular Manifestations in Newly Diagnosed Hyperthyroid Patients and their Outcome with Anti-Thyroid Treatment

Archana Sonawale1, Ashwin Chichkhede2

  • 1Associate Professor, Department of Medicine, Seth G.S. Medical College and K.E.M. Hospital, Mumbai, Maharashtra; *Corresponding Author.

The Journal of the Association of Physicians of India
|July 24, 2019
PubMed

Insights

Cardiovascular issues are common in new hyperthyroid patients. Anti-thyroid therapy effectively treats these abnormalities, preventing lasting heart damage.

Area of Science:

  • Endocrinology
  • Cardiology
  • Internal Medicine

Background:

  • Hyperthyroidism frequently presents with cardiovascular complications.
  • Understanding the incidence and treatment outcomes of these abnormalities is crucial.

Purpose of the Study:

  • To determine the frequency of cardiovascular abnormalities in newly diagnosed hyperthyroid patients.
  • To assess the effectiveness of anti-thyroid therapy on these abnormalities.

Main Methods:

  • 96 newly diagnosed hyperthyroid patients were screened; 40 with cardiovascular symptoms were included.
  • Patients underwent cardiovascular history, physical examination, ECG, and 2D ECHO.
  • Evaluations were performed at presentation and after 3 months of anti-thyroid treatment.

Main Results:

  • Cardiovascular symptoms, hemodynamic changes, and dysrhythmias (especially supraventricular) were common.
  • Palpitations and atrial fibrillation (AF) were more frequent in overt hyperthyroidism.
  • These abnormalities persisted in some patients with persistently high thyroid hormone levels after treatment.

Conclusions:

  • Cardiovascular abnormalities are a frequent manifestation of hyperthyroidism.
  • Treatment with anti-thyroid drugs is effective in resolving these issues before structural cardiac changes occur.
Abstract

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