Microbicide surface nano-structures
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Updated: Jan 21, 2026

Structural Information from Single-molecule FRET Experiments Using the Fast Nano-positioning System
Published on: February 9, 2017
Guangshun Yi1, Siti Nurhanna Riduan1, Yuan Yuan1
1a Institute of Bioengineering and Nanotechnology, The Nanos , Singapore , Singapore.
Abstract:
The prevention of infectious diseases is a global challenge where multidrug-resistant bacteria or "superbugs" pose a serious threat to worldwide public health. Microtopographic surfaces have attracted much attention as they represent a biomimetic and nontoxic surface antibacterial strategy to replace biocides. The antimicrobial effect of such natural and biomimetic surface nanostructures involves a physical approach which eradicates bacteria via the structural features of the surfaces without any release of biocides or chemicals. These recent developments present a significant proof-of-concept and a powerful tool in which cellular adhesion and death caused by a physical approach, can be controlled by the micro/nanotopology of such surfaces. This represents an innovative direction of development of clean, effective and nonresistant antimicrobial surfaces. The minireview will cover novel approaches for the construction of nanostructures on surfaces in order to create antimicrobial surface in an environmentally friendly, nontoxic manner.
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