A Randomized Trial of Ultrasound- versus. Fluoroscopy-Guided Subclavian Vein Catheterization in Children with

Huajin Pang1, Yong Chen2, Xuehan Liu3

  • 1Department of Interventional Radiology, Nanfang Hospital, Southern Medical University, Guangzhou, China. nfyyphj@163.com.

Insights

Ultrasound guidance improves subclavian vein catheterization success in children with hematologic diseases. Combining ultrasound and fluoroscopy may offer the most efficient approach for this pediatric population.

Area of Science:

  • Pediatric Hematology
  • Vascular Access Procedures
  • Medical Imaging Techniques

Background:

  • Subclavian vein catheterization is crucial for pediatric patients with hematologic diseases.
  • Accurate and safe venous access is essential for treatment delivery and patient outcomes.
  • Current guidance methods include ultrasound and fluoroscopy, each with potential benefits and drawbacks.

Purpose of the Study:

  • To compare the efficacy and safety of ultrasound-guided versus fluoroscopy-guided subclavian vein catheterization in pediatric patients with hematologic diseases.
  • To evaluate key outcomes such as cannulation success, procedural time, and complication rates.

Main Methods:

  • A randomized prospective study involving 170 pediatric patients with hematologic diseases.
  • Patients were randomly assigned to either ultrasound-guided or fluoroscopy-guided subclavian vein catheterization.
  • Primary outcome: number of attempts for venous cannulation; Secondary outcomes: success rate, fluoroscopy time, operation time, and complications.

Main Results:

  • Ultrasound guidance resulted in a significantly higher success rate within 3 attempts (92.0%) compared to fluoroscopy (78.3%).
  • No significant differences were observed in average operation time or overall surgical complications between the groups.
  • While the fluoroscopy group had no catheter-related thrombosis (CRT), the ultrasound group had 4 CRTs during follow-up.

Conclusions:

  • Ultrasound-guided venous puncture offers superior accuracy for subclavian vein catheterization in this pediatric cohort.
  • Fluoroscopy provides greater precision for catheter tip placement.
  • A combined ultrasound- and fluoroscopy-guided approach is suggested to enhance efficiency in subclavian vein catheterization for children with hematologic disease.
Abstract

Related Concept Videos

Cardiac Catheterization II: Right Heart Catheterization01:21

Cardiac Catheterization II: Right Heart Catheterization

Right Heart Catheterization: An OverviewRight heart catheterization is an invasive diagnostic procedure that measures right-sided cardiac and pulmonary artery pressures, calculates cardiac output, and identifies intracardiac shunts. It provides detailed hemodynamic data essential for diagnosing and managing various cardiovascular conditions, such as pulmonary hypertension.Access SitesCommon access sites for right heart catheterization include the internal jugular vein in the neck region, the...
860
Cardiac Catheterization III: Left Heart Catheterization01:24

Cardiac Catheterization III: Left Heart Catheterization

Left heart catheterization is an invasive diagnostic procedure used to evaluate the function and structure of the left side of the heart. It is generally performed to diagnose and treat cardiovascular conditions such as valve abnormalities, coronary artery disease, and congenital heart defects.Diagnostic and therapeutic purposesLeft heart catheterization serves various diagnostic and therapeutic purposes, including:Assessing coronary artery bypass grafts.Evaluating coronary artery disease in...
611
Clinical Trials01:16

Clinical Trials

Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.2K
Clinical Trials: Overview01:11

Clinical Trials: Overview

Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
4.6K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
399
Random Error01:04

Random Error

Random or indeterminate errors originate from various uncontrollable variables, such as variations in environmental conditions, instrument imperfections, or the inherent variability of the phenomena being measured. Usually, these errors cannot be predicted, estimated, or characterized because their direction and magnitude often vary in magnitude and direction even during consecutive measurements. As a result, they are difficult to eliminate. However, the aggregate effect of these errors can be...
9.1K