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Genetic Encoding of a Non-Canonical Amino Acid for the Generation of Antibody-Drug Conjugates Through a Fast Bioorthogonal Reaction
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Engineering Dual Variable Domains for the Generation of Site-Specific Antibody-Drug Conjugates

Alex R Nanna1,2, Christoph Rader3

  • 1Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL, USA.

Methods in Molecular Biology (Clifton, N.J.)
|July 24, 2019
PubMed

Keywords:
Antibody–drug conjugateCatalytic antibodyDrug-to-antibody ratioDual-variable-domainHomogeneousSite-specific conjugation

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