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Updated: Jan 21, 2026

Tail Vein Transection Bleeding Model in Fully Anesthetized Hemophilia A Mice
Published on: September 30, 2021
A rare cause of rectal bleeding
Ana Santos1, Armando Peixoto2, Guilherme Macedo2
1Gastrenterologia, Centro Hospitalar de São João, Portugal.
Abstract:
A 54-year-old male patient, with recent medical history of acute myocardial infarction, performed a colonoscopy in context of rectal bleeding that revealed, in the sigmoid and rectum colon, erythematous and hemorrhagic lesions, with high friability to the touch, surrounded by normal mucosa. Histologically, the lesions was compatible with a chronic inflammatory process, with eosinophilic structures and hyaline material evident, characterized as amyloid substance after staining with Congo Red. The authors describe the present clinical case because of its rarity, highlighting the importance of a careful differential diagnosis in the approach of these clinical signs present in the daily practice of Gastroenterology.
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