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Updated: Aug 11, 2026

Methods to Inhibit Bacterial Pyomelanin Production and Determine the Corresponding Increase in Sensitivity to Oxidative Stress
Published on: August 31, 2015
The influence of pyrithione on the growth of micro-organisms
M M Khattar1, W G Salt, R J Stretton
1Department of Chemistry, Loughborough University of Technology, Leicestershire, UK.
Abstract:
Pyrithione was active against a range of micro-organisms, the most resistant being Gram-negative bacteria. The growth curves for Klebsiella pneumoniae and Bacillus licheniformis showed a drug-dependent lag phase. Candida albicans grew with a drug-dependent growth rate. EDTA antagonized the effects of pyrithione.
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