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Published on: August 19, 2025
Anthropometric Changes in a Prospective Study of 100 Patients Requesting Breast Reduction
Donald A Hudson1, Ngoato B Lelala1
1Department of Plastic and Reconstructive Surgery, University of Cape Town, Cape Town, South Africa.
Nipple asymmetry and inframammary fold descent are common in macromastia, particularly with higher BMI. Lateral nipple displacement is frequent and worsens with increased body mass index.
Area of Science:
- Plastic Surgery
- Human Anatomy
- Medical Research
Background:
- Standard breast anthropometry is well-documented.
- Changes in breast shape with macromastia are less understood.
- Macromastia is defined as excessive mammary gland development.
Purpose of the Study:
- Assess nipple asymmetry prevalence in the horizontal plane for patients with macromastia.
- Evaluate changes in the inframammary fold (IMF) in patients with macromastia.
- Investigate the relationship between body mass index (BMI) and these anatomical changes.
Main Methods:
- 100 patients (200 breasts) undergoing bilateral breast reduction were studied.
- Collected data included age, BMI, and specific breast measurements (nipple to IMF, etc.).
- Univariate statistical analyses were used to assess nipple asymmetry's impact.
Main Results:
- Average age was 37 years; median BMI was 33.
- Nipple asymmetry was observed in 45% lateral, 19% medial, and 36% central positions.
- Higher BMI correlated with lateral/medial asymmetry; increased breast size and BMI correlated with IMF descent.
Conclusions:
- Nipple displacement, especially lateral, is common in macromastia and linked to higher BMI.
- Inframammary fold descent is also prevalent and associated with increased BMI.
- These findings have significant clinical implications for breast reduction surgery.
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