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Apert syndrome patients showed similar hand outcomes regardless of hand type after surgery. However, their scores were lower than those of age-matched controls, indicating a persistent impact of the condition.

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Area of Science:

  • Congenital Hand Deformities
  • Pediatric Orthopedics
  • Plastic Surgery

Background:

  • The Michigan Hand Questionnaire (MHQ) is a standard tool for evaluating hand function in congenital hand deformities.
  • Apert syndrome is a complex congenital condition affecting hand development.
  • Understanding hand outcomes in Apert syndrome is crucial for surgical planning and patient care.

Purpose of the Study:

  • To compare hand outcomes in Apert syndrome patients based on Upton hand type and age.
  • To evaluate Apert syndrome hand outcomes against age-matched unaffected controls.

Main Methods:

  • The Brief Michigan Hand Questionnaire was administered to 39 Apert patients post-surgery and 140 controls.
  • Apert patients were stratified by age (infants/children, adolescents, adults) and Upton hand type (I, II, III).
  • Parental or patient responses were utilized based on age group.

Main Results:

  • No statistically significant differences in hand outcomes were found among Apert patients based on Upton hand type across all age groups.
  • Apert syndrome patients demonstrated significantly lower hand outcome scores compared to age-matched controls (P < 0.05).

Conclusions:

  • Hand outcomes in Apert syndrome are consistent across different Upton hand types following digit separation surgery.
  • Despite surgical intervention, Apert syndrome patients exhibit diminished hand function compared to the general population.