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Updated: Jan 21, 2026

Assessing Corticospinal Excitability During Goal-Directed Reaching Behavior
Published on: December 2, 2022
Hemodynamic early goal-directed therapy: Explaining the fine print
Zoe Goldthwaite1, Michael S Firstenberg1, Alex Botsch2
1Department of Cardiothoracic and Vascular Surgery, The Medical Center of Aurora, Aurora, CO, USA.
Abstract:
The management of patients after cardiothoracic surgery can be very complex. Variabilities exist in hemodynamic status after cardiac surgery and the use of cardiopulmonary bypass - all of which can have a significant impact on myocardial Frank-Starling curves. Typically, invasive monitoring with pulmonary artery catheters is used to assess the complex physiology that these patients experience in the perioperative setting. However, the use of invasive monitoring is not without risk, and the broader benefits are poorly defined. Furthermore, there is growing evidence to support the use of hemodynamic early goal-directed therapy to optimize outcomes in critically ill patients. The purpose of this editorial statement is the review of some of the current literature with regards to the utility of goal-directed therapy as applied to the postoperative cardiac surgical patient.
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