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Central odontogenic fibroma.

S R Watt-Smith1, N G Ell-Labban, S M Tinkler

  • 1Institute of Dental Surgery Eastman Dental Hospital, London, United Kingdom.

International Journal of Oral and Maxillofacial Surgery
|April 1, 1988
PubMed
Summary
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A rare benign neoplasm, central odontogenic fibroma, was observed in a 63-year-old female. Ultrastructural analysis revealed myofibroblasts, offering insights into this rare jaw tumor.

Area of Science:

  • Oral pathology
  • Neoplastic pathology
  • Fibroblastic lesions

Background:

  • Central odontogenic fibroma is a rare, benign jaw neoplasm.
  • This case presents a unique instance in the mandible of a 63-year-old female.
  • Understanding the cellular origins and characteristics is crucial for diagnosis.

Observation:

  • The lesion affected the left mandibular molar region.
  • Histological examination showed fibroblast-like cells in a myxomatous collagenous stroma.
  • Odontogenic epithelium islands were also noted.

Findings:

  • Ultrastructural analysis revealed tumor cells with fine filaments and focal densities.
  • These cellular features resemble smooth muscle cells.
  • The presence of a moderately developed rough endoplasmic reticulum (r ER) was observed.

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Implications:

  • The findings suggest the tumor cells are myofibroblasts.
  • This contributes to the understanding of rare odontogenic tumors.
  • Further research into myofibroblast differentiation in odontogenic lesions is warranted.