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Making a national donor research program a reality: Concepts for operationalizing a system

Richard B Freeman1,2

  • 1Dell Medical School, University of Texas at Austin, Austin, Texas.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
|July 24, 2019
PubMed

Insights

Establishing a National Donor Research Program is crucial for enhancing deceased donor organ utilization and function. This paper outlines an operational framework to overcome existing research barriers and improve outcomes.

Area of Science:

  • Transplantation research
  • Organ donation science
  • Medical research infrastructure

Background:

  • Deceased donor research is vital for improving organ utilization and function.
  • Significant barriers impede the successful conduct of deceased donor research trials.
  • Existing reports offer a framework for a National Donor Research Program.

Purpose of the Study:

  • To propose an operational model for a National Donor Research Program.
  • To address the challenges hindering deceased donor research.
  • To provide a practical viewpoint on program implementation.

Main Methods:

  • Review of existing reports and frameworks.
  • Analysis of barriers to deceased donor research.
  • Development of an operational viewpoint for program establishment.

Main Results:

  • Identified key barriers to deceased donor research.
  • Proposed a framework for a National Donor Research Program.
  • Outlined an operational perspective for program implementation.

Conclusions:

  • A structured National Donor Research Program is essential.
  • Operationalizing such a program requires addressing identified barriers.
  • This viewpoint offers a pathway toward enhanced organ utilization.
Keywords:
clinical research/practicedonors and donation: deceaseddonors and donation: donation after brain death (DBD)donors and donation: donor evaluationeditorial/personal viewpointorgan procurement and allocationorgan transplantation in general, donors and donation

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