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Related Concept Videos

Eccentric Loading01:16

Eccentric Loading

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Eccentric loading is a crucial concept in the study of structural engineering and mechanics, particularly when analyzing the stability and stress distribution in columns. Unlike centric loading, where the force is applied along the centroidal axis, causing uniform compression, eccentric loading occurs when a force is applied off-center. This off-center application introduces not only direct compressive stress but also bending stress, significantly influencing the column's behavior under...
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Transcription Attenuation in Prokaryotes02:42

Transcription Attenuation in Prokaryotes

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Transcriptional attenuation occurs when RNA transcription is prematurely terminated due to the formation of a terminator mRNA hairpin structure.  Bacteria use these hairpins to regulate the transcription process and control the synthesis of several amino acids including histidine, lysine, threonine, and phenylalanine. Transcription attenuation takes place in the non-coding regions of mRNA.
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General Case of Eccentric Axial Loading01:12

General Case of Eccentric Axial Loading

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Unsymmetrical bending occurs when the bending moment applied to a structural member does not align with its principal axis. This misalignment leads to complex stress distributions and deflection patterns that differ from symmetrical bending, which are essential for designing structures to withstand different loading conditions.
Consider a member subjected to equal and opposite forces that are applied along a line that does not coincide with the member's neutral axis. In unsymmetrical...
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Decreased Body Temperature01:29

Decreased Body Temperature

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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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Decreased pulse rate01:14

Decreased pulse rate

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Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
There are specific risk factors that can elevate the likelihood of developing bradycardia. Advanced age is a significant factor, with...
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Design of Columns under an Eccentric Load01:21

Design of Columns under an Eccentric Load

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Designing columns to withstand eccentric loads is a critical aspect of structural engineering, ensuring structures can support off-center loads without failure. This design process must account for the additional normal stresses introduced by eccentric loading, which can significantly influence a column's stress distribution and overall stability. An eccentric load applied to a column induces normal stresses that can be conceptualized as a combination of stresses due to an equivalent...
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Related Experiment Video

Updated: Jan 21, 2026

Muscle Imbalances: Testing and Training Functional Eccentric Hamstring Strength in Athletic Populations
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Curcumin supplementation attenuates the decrease in endothelial function following eccentric exercise.

Youngju Choi, Yoko Tanabe, Nobuhiko Akazawa

    Journal of Exercise Nutrition & Biochemistry
    |July 25, 2019
    PubMed
    Summary

    Acute curcumin supplementation prevented exercise-induced endothelial dysfunction in healthy men. Curcumin intake before eccentric exercise maintained vascular endothelial function, measured by brachial artery flow-mediated dilation (FMD).

    Keywords:
    supplementation

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    Area of Science:

    • Exercise Physiology
    • Nutritional Biochemistry
    • Vascular Biology

    Background:

    • Eccentric exercise can impair vascular endothelial function.
    • Curcumin, from turmeric, possesses antioxidant and anti-inflammatory properties.
    • These properties suggest a potential role in vascular protection.

    Purpose of the Study:

    • To investigate the effect of acute curcumin supplementation on endothelial dysfunction induced by eccentric exercise.
    • To assess changes in brachial artery flow-mediated dilation (FMD) following exercise.

    Main Methods:

    • A randomized controlled trial involving 14 healthy young men.
    • Participants received either curcumin or a placebo before performing eccentric elbow flexor exercise.
    • Brachial artery FMD was measured pre- and post-exercise in the non-exercised arm.

    Main Results:

    • Eccentric exercise significantly reduced FMD in the placebo group.
    • Curcumin supplementation before exercise prevented this significant decrease in FMD.
    • A significant difference in FMD change was observed between the curcumin and placebo groups.

    Conclusions:

    • Acute curcumin intake can attenuate exercise-induced reductions in endothelial function.
    • Curcumin may protect vascular endothelial function following eccentric exercise in young men.