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The effect of lithium administration on LH response in healthy volunteers
1Department of Neurosciences, McMaster University, Hamilton, Ontario, Canada.
Progress in Neuro-Psychopharmacology & Biological Psychiatry
|January 1, 1988
Abstract:
1. As part of a systematic investigation of the effects of lithium administration on neuroendocrine function we investigated the luteinizing hormone (LH) response to luteinizing hormone releasing hormone (LHRH) of healthy males. 2. In healthy volunteers after 3 weeks of therapeutic doses of lithium the LH response to LHRH was significantly increased in comparison with the responses prior to lithium administration. 3. An attempt is made to explain these findings by underlying neurotransmitter changes.