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Tea consumption and risk of fractures: an updated meta-analysis
1Department of Epidemiology and Health Statistics, The School of Public Health of Qingdao University, No. 38 Dengzhou Road, Qingdao, 266021, Shandong, People's Republic of China.
Abstract:
This meta-analysis included 16 studies, involving seven cohort studies and nine case-control studies, and the results indicated that tea consumption may be associated with a reduced the risk of fractures.
Introduction:
Regarding relationship of tea consumption with the risk of fractures remains controversial. We performed a meta-analysis to elucidate the association between tea consumption and the risk of fractures.
Methods:
Relevant articles were identified up to March 2019 by searching PubMed, Web of Science, and Embase databases. The pooled relative risks (RRs) with 95% confidence intervals (CIs) were computed utilizing fixed or random effects model based on heterogeneity.
Results:
Altogether 16 studies (seven cohort and nine case-control studies) were included in this meta-analysis, involving 772,707 participants with 37,166 fracture cases. The RRs (95% CIs) of fracture for the highest versus lowest category of tea consumption were 0.86 (0.78-0.94). Subgroup analysis indicated significant associations in cohort studies (0.90 (0.86-0.94)) and case-control studies (0.77 (0.69-0.85)).
Conclusions:
The current meta-analysis indicates that tea consumption may be associated with a reduced the risk of fractures.
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