Related Experiment Video
Updated: Jan 21, 2026
Synthesis of Indoxyl-glycosides for Detection of Glycosidase Activities
Published on: May 27, 2015
New Anti-inflammatory Triterpene Esters and Glycosides from Alstonia scholaris
Nighat Sultana1, Muhammad Saleem Qazi1,2, Mustafa Kamal2
1Pharmaceutical Research Center, PCSIR Laboratories Complex, Karachi, Pakistan.
Background:
Phytochemical studies on the ethanolic extract of aerial parts of Alstonia scholaris lead to the isolation of two new triterpenoid of the lanostanetype, lanosta 5ene,24-ethyl-3-O-β-D-glucopyranoside (1), lanosta,5ene,24-ethyl-3-O-β-D-glucopyranosideester (2) and new ursane type triterpenoidmethylester, 12-ursene-2,3,18,19-tetrol,28 acetate (nighascholarene) (3), together with seven known triterpenes, betuline, triterpene of the lupane type, alstoprenyol (4), 3β-hydroxy-28-β-acetoxy-5-olea triterpene (5),α-amyrin acetate (6), α-amyrin (7), lupeol acetate (8), 3β-hydroxy-24-nor-urs-4,12,28-triene triterpene (9) and ursolic acid (l0).
Methodology:
The triterpenoid structures of these colorless compounds were deduced from the 1H and 13C-NMR data, and in particular from the application of two-dimensional 1H, 13C correlation experiments as well as by comparison with reported literature data.
Conclusion:
This study deals with isolation and structural elucidation of natural new triterpenoidesters and glycosides with anti-inflammatory activity.
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