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Double-blind crossover study comparing sodium cromoglycate, reproterol, reproterol plus sodium cromoglycate, and
1Clinic for Lung Diseases, Asthma and Allergy Auguste-Viktoria- and Cecilienstift, Bad Lippspringe, West Germany.
Annals of Allergy
|July 1, 1988
Abstract:
Sixteen patients were included in the analysis of this double-blind crossover study comparing the effect of sodium cromoglycate, reproterol, sodium cromoglycate plus reproterol, and placebo in exercise-induced asthma. Both the sodium cromoglycate and the reproterol-containing treatment significantly inhibited exercise-induced asthma. The best protection is effected by the combination of sodium cromoglycate and reproterol. A synergistic effect of both medications could not be confirmed statistically so that their combined effect is simply additive.