Related Experiment Video

Updated: Jul 25, 2026

Dissection of Single Skeletal Muscle Fibers for Immunofluorescent and Morphometric Analyses of Whole-Mount Neuromuscular Junctions
08:41

Dissection of Single Skeletal Muscle Fibers for Immunofluorescent and Morphometric Analyses of Whole-Mount Neuromuscular Junctions

Published on: August 14, 2021

Bridging structures spanning the junctioning gap at the triad of skeletal muscle

A V Somlyo

    The Journal of Cell Biology
    |March 1, 1979
    PubMed

    Keywords:
    junctional gapskeletal muscle ultrastructuretransverse tubulesarcoplasmic reticulum

    More Related Videos

    Functional Site-Directed Fluorometry in Native Cells to Study Skeletal Muscle Excitability12:26

    Functional Site-Directed Fluorometry in Native Cells to Study Skeletal Muscle Excitability

    Published on: June 2, 2023

    Intact Short, Intermediate, and Long Skeletal Muscle Fibers Obtained by Enzymatic Dissociation of Six Hindlimb Muscles of Mice: Beyond Flexor Digitorum Brevis08:12

    Intact Short, Intermediate, and Long Skeletal Muscle Fibers Obtained by Enzymatic Dissociation of Six Hindlimb Muscles of Mice: Beyond Flexor Digitorum Brevis

    Published on: December 1, 2023

    Related Concept Videos

    Skeletal Muscle Anatomy00:55

    Skeletal Muscle Anatomy

    Skeletal muscle is the most abundant type of muscle in the body. Tendons are the connective tissue that attaches skeletal muscle to bones. Skeletal muscles pull on tendons, which in turn pull on bones to carry out voluntary movements.
    Cross-bridge Cycle01:26

    Cross-bridge Cycle

    As muscle contracts, the overlap between the thin and thick filaments increases, decreasing the length of the sarcomere—the contractile unit of the muscle—using energy in the form of ATP. At the molecular level, this is a cyclic, multistep process that involves binding and hydrolysis of ATP, and movement of actin by myosin.
    The Sarcomere01:08

    The Sarcomere

    A sarcomere is a microscopic segment repeating in a myofibril. The sarcomere fundamentally consists of two main myofilaments: thick filaments called myosin and thin filaments called actin. These filaments interact by sliding past each other in response to stimulus. In addition to myosin and actin, several other proteins, such as tropomyosin, troponin, titin, nebulin, myomesin, α-actinin, and dystrophin, play crucial roles in regulating, structuring, and functioning of the sarcomere.
    Each myosin...
    Excitation-Contraction Coupling in Skeletal Muscles01:20

    Excitation-Contraction Coupling in Skeletal Muscles

    Excitation-contraction coupling is a series of events that occur between generating an action potential and initiating a muscle contraction. It occurs at the triad, a structure found in skeletal muscle fibers that comprise a T-tubule and terminal cisternae of the sarcoplasmic reticulum on each side. These triads are visible in longitudinally sectioned muscle fibers. They are typically located at the A-I junction — the junction between the A and I bands of the sarcomere.
    When an action potential...
    Structure of Cardiac Muscles01:13

    Structure of Cardiac Muscles

    Cardiac muscle, or myocardium, is a specialized type of muscle found exclusively in the heart. Its unique structural and functional characteristics enable the heart to perform its vital role of pumping blood throughout the body continuously and rhythmically. The cardiac muscle cells, or cardiomyocytes, possess an endomysium and perimysium but do not have an epimysium.
    Compared to skeletal muscles, cardiac muscle cells are small and mostly have a single nucleus. Additionally, they are usually...
    Fascicle Arrangement in Skeletal Muscles01:25

    Fascicle Arrangement in Skeletal Muscles

    Fascicles are bundles of muscle fibers in a skeletal muscle. Muscle fascicle arrangement is directly associated with the power and range of motion of various muscles. The configuration of these fascicles can vary, leading to different functional outcomes.
    The four primary types of muscle based on fascicle arrangement are: