Aggressive Surgical Resection of Enormous Cervical Metastasis from Nasopharyngeal Carcinoma
Related Experiment Video For Cervical Metastasis
Updated: Jan 21, 2026

A "Patient-Like" Orthotopic Syngeneic Mouse Model of Hepatocellular Carcinoma Metastasis
Published on: October 24, 2015
Sha Fu1, Jin-Song Li2,3, Eduardo Dias-Ribeiro4
1Department of Pathology, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou 510120, China.
Abstract:
While nasopharyngeal carcinoma (NPC) commonly presents lymphoid metastases, the enormous cervical metastasis causing dysphagia and limitation of neck motion is not a familiar symptom for most of NPC cases. We report a 23-year-old male with undifferentiated carcinoma of the nasopharynx, stage III (T3N2M0), who had undergone aggressive surgical resection of bilateral huge cervical mass first followed by concurrent chemo-radiotherapy with cisplatin-based regimens. The postoperative clinical course was uneventful and follow-up, 2 years later, revealed no recurrence of primary lesion and neck metastases. We recommend that aggressive surgical resection may be considered when NPC patients significantly suffer clinical symptoms from a huge cervical metastasis.
Related Concept Videos
Aggression
Suctioning the Nasopharyngeal Airway
Equipment Required
Metastasis
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
Secondary Motives: Affiliation Motivation and Aggression Motivation
Kidney Transplant II: Surgical Procedure
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:

