Related Experiment Video
Updated: Jan 21, 2026

12:16
Quantitative Measurement of the Immune Response and Sleep in Drosophila
Published on: December 4, 2012
15.9K
Sleep: A Pathway Linking Personality to Mortality Risk.
Shantel K Spears1, Hawley E Montgomery-Downs1, Shari Steinman1
1West Virginia University, 1124 Life Sciences Building, Morgantown, West Virgina, 26506-6040 United States.
Journal of Research in Personality
|July 26, 2019
Summary
Personality traits and sleep patterns influence longevity. This study reveals sleep duration mediates how conscientiousness affects mortality risk, with implications for health interventions.
Area of Science:
- Psychology
- Gerontology
- Epidemiology
Background:
- Personality traits and sleep are known predictors of longevity.
- The mediating role of sleep in the association between personality and mortality has not been previously investigated.
- Understanding these relationships is crucial for developing targeted health interventions.
Purpose of the Study:
- To examine whether sleep mediates the relationship between personality traits and longevity.
- To investigate the direct and indirect effects of personality on mortality risk through sleep patterns and daytime dysfunction.
Main Methods:
- Longitudinal study with a 20-year follow-up.
- Utilized data from the Midlife Development in the United States cohort (N = 3,759).
- Employed proportional hazards and structural equation modeling to analyze personality, sleep duration, daytime dysfunction, and mortality risk.
Main Results:
- Lower conscientiousness was associated with increased death risk, mediated by quadratic sleep duration.
- Higher neuroticism and agreeableness, and lower conscientiousness predicted increased mortality risk through combined effects of sleep duration and daytime dysfunction.
- Lower extraversion predicted increased mortality risk indirectly via daytime dysfunction.
Conclusions:
- Sleep duration acts as a mediator between personality traits and mortality risk.
- Specific personality traits influence longevity through complex pathways involving sleep and daytime functioning.
- Findings support the development of personality-based health strategies to promote longevity.
Related Concept Videos
Insufficient Sleep and Sleep Deprivation
850
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
850
Covalently Linked Protein Regulators
8.7K
Proteins can undergo many types of post-translational modifications, often in response to changes in their environment. These modifications play an important role in the function and stability of these proteins. Covalently linked molecules include functional groups, such as methyl, acetyl, and phosphate groups, and also small proteins, such as ubiquitin. There are around 200 different types of covalent regulators that have been identified.
These groups modify specific amino acids in a protein....
These groups modify specific amino acids in a protein....
8.7K
Enzyme-linked Receptors
86.2K
Enzyme-linked receptors are proteins that act as both receptor and enzyme, activating multiple intracellular signals. This is a large group of receptors that include the receptor tyrosine kinase (RTK) family. Many growth factors and hormones bind to and activate the RTKs.
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...
Neurotrophin (NT) receptors are a family of RTKs, including trkA, trkB, and trkC (tropomyosin-related kinase) receptors. TrkA is specific for nerve growth factor (NGF), neurotrophin-6, and neurotrophin-7. TrkB binds...
86.2K
Stages of Sleep
1.3K
Sleep progresses through distinct stages, each characterized by specific brain wave patterns and physiological responses ranging from wakefulness to stages of non-rapid eye movement, known as non-REM, to rapid eye movement, referred to as REM. Understanding these stages helps in recognizing how sleep supports various bodily and cognitive functions.
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
Before sleep begins, in wakefulness, the brain exhibits primarily beta waves, which are high in frequency and low in amplitude, indicating alertness...
1.3K
C4 Pathway and CAM
48.8K
Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy.
C4 Pathway
The C4 pathway is used by plants such as...
C4 Pathway
The C4 pathway is used by plants such as...
48.8K
Relative Risk
2.0K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.0K

