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The Clinical Application Value of Multiple Combination Food Intolerance Testing
Shudong Lin1, Xiujing Yang1, Ying Xing1
1Clinical Laboratory, The Third Affiliated Hospital of Qiqihar Medical University, Qiqihar, P.R. China.
Iranian Journal of Public Health
|July 26, 2019
Summary
Detecting food-specific IgG antibodies aids in identifying food intolerances. This method helps manage health by avoiding trigger foods and offers a new approach for disease diagnosis and prevention.
Area of Science:
- Immunology
- Clinical Medicine
- Dietary Science
Background:
- Food intolerances affect a significant portion of the population, leading to various health issues.
- Accurate diagnosis of food intolerances is crucial for effective management and prevention of related diseases.
Purpose of the Study:
- To evaluate the clinical utility of detecting 14 food-specific immunoglobulin G (IgG) antibodies for diagnosing food intolerances.
- To analyze the prevalence and clinical significance of food-specific IgG antibodies in a patient cohort.
Main Methods:
- Enzyme-linked immunosorbent assay (ELISA) was employed to detect specific IgG antibodies against 14 common foods.
- A cohort of 312 patients with suspected food intolerance was recruited from February 2016 to February 2017.
Main Results:
- Crab (42.31%), shrimp (21.15%), egg (18.27%), and milk (16.99%) showed the highest positive IgG antibody rates.
- Significant differences in IgG antibody positivity were observed across different symptom groups (skin, gastrointestinal, respiratory, nervous system) and age groups (adolescent, middle-aged, elderly).
Conclusions:
- Detection of food-specific IgG antibodies can assist in identifying causative foods for intolerances.
- This diagnostic approach offers a novel strategy for the prevention and management of diseases linked to food intolerances, enabling personalized dietary interventions.
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