Related Experiment Video
Updated: Jan 21, 2026
14:03
Micro-drive Array for Chronic in vivo Recording: Drive Fabrication
Published on: April 20, 2009
25.8K
Aging Well: Using Precision to Drive Down Costs and Increase Health Quality
Rhoda Au1,2,3,4, Marina Ritchie4, Spencer Hardy4
1Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA.
Advances in Geriatric Medicine and Research
|July 26, 2019
Summary
Precision medicine alone cannot combat rising chronic diseases. Integrating data science and AI for digital biomarkers can shift healthcare to precision health, enabling early disease detection and prevention.
Area of Science:
- Digital Health
- Biomarkers
- Healthcare Innovation
Background:
- Precision medicine advances have improved individualized treatments but fail to curb the rise of chronic non-communicable diseases in aging populations.
- Current healthcare models face challenges in managing increasing disease prevalence and healthcare costs.
- Early detection of disease indicators is crucial for effective intervention.
Purpose of the Study:
- To propose a shift from precision medicine to precision health.
- To explore the potential of data science and artificial intelligence in identifying digital biomarkers.
- To outline strategies for preventing chronic diseases and improving health quality.
Main Methods:
- Leveraging technological advancements for collecting digital metrics.
- Utilizing data science and artificial intelligence for discovering digital biomarkers.
- Analyzing current healthcare models and identifying challenges.
Main Results:
- Digital metrics can detect disease indicators earlier, potentially identifying pre-symptomatic stages.
- Data science and AI can uncover digital biomarkers before clinical symptoms manifest.
- A transition to precision health offers a path towards disease prevention.
Conclusions:
- A comprehensive precision health approach, driven by digital biomarkers, is essential for combating chronic diseases.
- Early detection through digital health technologies can redefine disease monitoring and prevention.
- Addressing current healthcare challenges requires a proactive strategy focused on preventing disease altogether.
Related Concept Videos
03:37Uncertainty in Measurement: Accuracy and Precision
100.2K
Scientists typically make repeated measurements of a quantity to ensure the quality of their findings and to evaluate both the precision and the accuracy of their results. Measurements are said to be precise if they yield very similar results when repeated in the same manner. A measurement is considered accurate if it yields a result that is very close to the true or the accepted value. Precise values agree with each other; accurate values agree with a true value.
100.2K
01:37Energy to Drive Translocation
2.7K
Mitochondrial protein import is powered by two distinct energy sources: ATP hydrolysis and electrochemical potential across the inner membrane. Newly synthesized precursors are bound by cytosolic chaperones of the Hsp70 family, which guide them to the import receptors on the mitochondrial surface. Utilizing the energy of ATP hydrolysis, Hsp70 chaperones transfer these precursors to the TOM receptors on the mitochondrial outer membrane.
Generally, polypeptides are unfolded by two distinct...
Generally, polypeptides are unfolded by two distinct...
2.7K
02:15M-Cdk Drives Transition Into Mitosis
6.4K
Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...
6.4K
01:26Aging
630
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
630
01:25Increased Body Temperature
6.4K
A body temperature above 38°C (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in...
6.4K
01:17Increased pulse rate
1.1K
Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
1.1K