Related Experiment Video
Updated: Jan 21, 2026

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Single-Port Robotic-assisted Transaxillary Breast-conserving Surgery: A Prospective, Single-arm, Non-randomized Phase IIa Clinical Trial
Published on: August 19, 2025
849
Update on the Feasibility and Progress on Robotic Breast Surgery.
Antonio Toesca1, Alessandra Invento2, Giulia Massari2
1Division of Breast Surgery, European Institute of Oncology IRCCS, Milan, Italy. antonio.toesca@ieo.it.
Annals of Surgical Oncology
|July 26, 2019
Summary
Robotic nipple-sparing mastectomy (RNSM) is a feasible and safe procedure with low complication rates and no early local recurrences. Further studies are needed to confirm long-term oncologic outcomes.
Area of Science:
- Oncologic Surgery
- Breast Surgery
- Robotic Surgery
Background:
- Robotic nipple-sparing mastectomy (RNSM) offers potential advantages in precision and cosmesis over open techniques.
- Limited data exist on the feasibility and safety of RNSM.
Purpose of the Study:
- To evaluate perioperative outcomes and early oncologic follow-up for patients undergoing RNSM.
- To assess the safety and efficacy of RNSM in a consecutive patient series.
Main Methods:
- Consecutive patients underwent RNSM with immediate robotic breast reconstruction via an axillary incision.
- Perioperative data, complications, pathological findings, and survival rates were recorded and analyzed.
- Follow-up data included local recurrence-free, disease-free, and overall survival.
Main Results:
- 94 RNSM procedures were performed on 73 women for various breast conditions.
- Mean operative time was 3 hours 32 minutes, with 89.4% undergoing one-step implant reconstruction.
- Low complication rates (4.3% reoperation, 1.1% flap necrosis) and no local recurrences were observed at a median 19-month follow-up.
Conclusions:
- RNSM demonstrates technical feasibility and safety with a low complication rate.
- Early oncologic outcomes are promising, with no local failures reported.
- Long-term follow-up is essential to validate oncologic safety; further trials are warranted.
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