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Updated: Jan 21, 2026

Purification of a High Molecular Mass Protein in Streptococcus mutans
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Purification of a High Molecular Mass Protein in Streptococcus mutans

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Sortase A-mediated modification of the Streptococcus mutans transcriptome and virulence traits

Xuan Chen1, Chengcheng Liu1,2, Xian Peng1

  • 1State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Sichuan University, Chengdu, China.

Molecular Oral Microbiology
|July 26, 2019
PubMed
Summary

Sortase A (SrtA) deletion in Streptococcus mutans enhances acid tolerance and reduces exopolysaccharide (EPS) production, impacting virulence. These changes are linked to altered gene transcription.

Keywords:
Streptococcus mutanssrtASortase Aacid toleranceexopolysaccharides productiontranscriptome

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