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[Takotsubo syndrome and hyperthyroidism: a case report].

A Irigaray Echarri¹, A Ernaga Lorea, N Eguilaz Esparza

¹Servicio de Endocrinología y Nutrición. Complejo Hospitalario de Navarra. Pamplona.. anairigarayecharri@gmail.com.

Anales Del Sistema Sanitario De Navarra

|July 26, 2019

Summary

This summary is machine-generated.

Stress cardiomyopathy (Takotsubo syndrome) mimics heart attacks but lacks blocked arteries. This case highlights hyperthyroidism as a potential trigger for Takotsubo syndrome, emphasizing the need for identifying predisposing factors.

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Area of Science:

Cardiology
Endocrinology

Background:

Stress cardiomyopathy, or Takotsubo syndrome, presents with symptoms mimicking acute coronary syndrome, including ECG changes and elevated troponin, but typically shows no obstructive coronary lesions.
Regional wall motion abnormalities on echocardiography are characteristic of Takotsubo syndrome.
Thyroid disorders have been associated with Takotsubo syndrome, though the underlying mechanism remains unclear.

Observation:

A case study of a woman presenting with acute chest pain, electrocardiographic abnormalities, and elevated troponin levels was observed.
Severe ventricular dysfunction was detected via echocardiography, with coronary arteriography revealing no obstructive lesions, consistent with Takotsubo syndrome.
The patient was diagnosed with hyperthyroidism due to Graves' disease, identified as the likely trigger for the Takotsubo syndrome.

Findings:

The presented case confirms the association between hyperthyroidism and Takotsubo syndrome.
Echocardiography revealed significant ventricular dysfunction, a hallmark of Takotsubo syndrome.
Coronary angiography excluded obstructive coronary artery disease, differentiating it from typical myocardial infarction.

Implications:

Identifying and managing clinical factors, such as hyperthyroidism, that may predispose patients to Takotsubo syndrome is crucial.
Understanding triggers like Graves' disease can improve the management and outcomes for patients with Takotsubo syndrome.
This case underscores the importance of considering endocrine disorders in the differential diagnosis of patients presenting with symptoms suggestive of acute coronary syndrome.