Neural oscillatory dynamics of inhibitory control in young adult binge drinkers

Alcohol consumption is often characterized by heavy episodic, or binge drinking, which has been on the rise. The aim of this study was to examine the neural dynamics of inhibitory control in demographically matched groups of young, healthy adults (N = 61) who reported engaging in binge (BD) or light drinking patterns (LD). Electroencephalography signal was recorded during a fast-paced visual Go/NoGo paradigm probing the ability to inhibit prepotent responses. No group differences were found in task performance. BDs showed attenuated event-related theta (4-7 Hz) on inhibition trials compared to LDs, which correlated with binge episodes and alcohol consumption but not with measures of mood or disposition including impulsivity. A greater overall decrease of early beta power (15-25 Hz) in BDs may indicate deficient preparatory "inhibitory brake" before deliberate responding. The results are consistent with deficits in the inhibitory control circuitry and are suggestive of allostatic neuroadaptive changes associated with binge drinking.