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Gestational Diabetes Mellitus

Emily D Szmuilowicz1, Jami L Josefson2, Boyd E Metzger3

  • 1Division of Endocrinology, Metabolism and Molecular Medicine, Department of Medicine, Northwestern University Feinberg School of Medicine, 645 North Michigan Avenue, 530-24, Chicago, IL 60611, USA.

Endocrinology and Metabolism Clinics of North America
|July 27, 2019
PubMed

Although it has been accepted for decades that women with gestational diabetes mellitus (GDM) are at high risk for future development of type 2 diabetes, vigorous debate regarding the value of detecting and treating GDM has persisted into the twenty-first century. Although results from 2 randomized trials provide strong evidence that treating GDM reduces adverse perinatal outcomes, it remains to be determined whether treatment impacts long-term offspring outcomes. Insulin is the first-line pharmacologic treatment and is added when glycemic goals are not met with nutritional modifications. Oral agent use is controversial, as data on long-term offspring outcomes are lacking.

Keywords:
DiagnosisGestational diabetes mellitusOffspringOutcomesPregnancyTreatment

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