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Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Diabetes Mellitus: Overview and Type I Subtype01:22

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
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Pathophysiology of Diabetes01:20

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Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
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Diabetes: Management and Pharmacotherapy01:15

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The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
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Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
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Diabetes: Symptoms, Diagnosis, and Complications01:15

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Related Experiment Video

Updated: Jan 21, 2026

A Protocol for Constructing a Rat Wound Model of Type 1 Diabetes
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Type 1 Diabetes in Pregnancy.

David R McCance1, Claire Casey1

  • 1Regional Centre for Endocrinology and Diabetes, Royal Victoria Hospital, Grosvenor Road, Belfast BT12 6BA, Northern Ireland, UK.

Endocrinology and Metabolism Clinics of North America
|July 27, 2019
PubMed
Summary
This summary is machine-generated.

Optimizing blood sugar control in pregnant women with type 1 diabetes is crucial but challenging. New technologies like Continuous Glucose Monitoring and insulin pumps offer improved glucose management, but their specific roles need further study.

Keywords:
Glycemic controlMaternal/fetal outcomesPregnancyType 1 diabetes

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Area of Science:

  • Reproductive Medicine
  • Endocrinology
  • Maternal-Fetal Medicine

Background:

  • Type 1 diabetes in pregnancy is associated with significantly higher rates of congenital malformations and perinatal mortality compared to the general population.
  • Pregnancy planning remains suboptimal among women with type 1 diabetes, despite the known risks.
  • Achieving optimal glycemic control is essential but difficult, requiring a careful balance to avoid hypoglycemia.

Purpose of the Study:

  • To review recent technological advancements in managing type 1 diabetes during pregnancy.
  • To discuss the potential of new technologies to improve glycemic control and reduce adverse outcomes.
  • To highlight the need for further research on the specific roles and indications for these advanced diabetes management tools.

Main Methods:

  • Review of recent technological advancements in diabetes management.
  • Discussion of Continuous Glucose Monitoring Systems (CGMS).
  • Evaluation of Continuous Subcutaneous Insulin Infusion (CSII) and Closed-Loop Systems (CLS).
  • Consideration of very Fast-Acting Insulin Aspart analogs.

Main Results:

  • New technologies like CGMS, CSII, CLS, and fast-acting insulins show promise for improving glucose control in selected patients.
  • These advancements offer new possibilities for increasing time spent within the target glucose range.
  • Further research is needed to elucidate the relative roles and optimal indications for these technologies.

Conclusions:

  • Advanced technologies present opportunities to enhance glycemic management in pregnant women with type 1 diabetes.
  • Careful patient selection and education are critical for the successful implementation of these tools.
  • Further elucidation of their roles and indications is necessary to maximize benefits and minimize risks.