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Updated: Aug 15, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
[Diagnosis and Treatment of Cognitive Impairment in Parkinson's Disease]
Tomotaka Shiraishi1, Hidetomo Murakami, Yasuyuki Iguchi
1Department of Neurology, The Jikei University School of Medicine.
Abstract:
Parkinson's disease (PD) patients can present with cognitive impairment, such as deficits in attention and memory processes, visual perception, executive function and social cognition. These dysfunctions negatively affect the activities of daily living and outcome of patients. Some of the risk factors, pathological background and etiology of cognitive dysfunction in PD with dementia (PDD) have been determined. Treatments for such dysfunctions are attracting much attention. Some medications, such as donepezil, rivastigmine, and memantine, have shown to improve motor and/or cognitive functions. Cognitive impairment and motor symptoms in PD can be treated concurrently. Therefore, the correlation between motor and cognitive function should be considered when treating PD.
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