Related Experiment Video
Updated: Jan 21, 2026

02:28
Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
777
Facial involvement and the severity of psoriasis
Adriana N Passos1, Vitória R P de A Rêgo1,2, Gleison V Duarte2
1Medical School of Bahia, Federal University of Bahia (FAMEB/UFBa), Salvador, BA, Brazil.
International Journal of Dermatology
|July 27, 2019
Summary
Facial psoriasis lesions indicate more severe disease. Identifying facial involvement is crucial for treatment decisions in psoriasis patients, impacting disease management and quality of life.
Area of Science:
- Dermatology
- Clinical Research
Background:
- Psoriasis is a chronic inflammatory skin condition affecting 0-6.6% globally.
- Facial lesions are often overlooked but may predict disease severity.
Purpose of the Study:
- To compare psoriasis severity (PASI) and quality of life (DLQI) in patients with and without facial lesions.
Main Methods:
- Cross-sectional study of 126 patients (63 with and 63 without facial lesions).
- Data collected from April 2014 to January 2016.
- Psoriasis Area and Severity Index (PASI) and Dermatology Life Quality Index (DLQI) were used for assessments.
Main Results:
- 50% of patients had facial lesions, most commonly on the pinna.
- Mean PASI was 14.0 (with facial lesions) vs. 6.0 (without).
- Mean DLQI was 7.5 (with facial lesions) vs. 4.7 (without).
Conclusions:
- Facial involvement in psoriasis is a significant marker of increased disease severity.
- Identifying facial lesions is important for guiding therapeutic decisions in psoriasis management.
Related Concept Videos
Facial Feedback Hypothesis
616
Charles Darwin proposed that facial expressions are an evolutionary adaptation for communication. He argued that these expressions are not influenced by culture but are universal across species. For example, a snarling expression with exposed teeth signals a threat in many animals, including humans. Darwin also suggested that displaying an emotion can intensify the feeling. Smiling, for example, could enhance one's sense of happiness. This idea laid the foundation for understanding the role...
616
Muscles for Facial Expressions
4.8K
The craniofacial muscles are a collection of approximately 20 thin skeletal muscles situated beneath the skin of the face and scalp. These muscles, primarily responsible for the vast array of human facial expressions, originate from the bones or fibrous structures of the skull and extend outwards to connect with the skin. While most skeletal muscles in the body are enveloped in thick fascia, facial muscles generally have a more delicate fascial covering, with the buccinator muscle being a...
4.8K
Antigens Involved in Adaptive Immunity
1.3K
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
Complete Antigens
Complete antigens possess both immunogenicity and...
1.3K
Nonconscious Mimicry
5.1K
Nonconscious mimicry occurs when individuals alter their mannerisms to match the behaviors and expressions of those nearby, without intention.
5.1K
Global Climate Change
28.7K
Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
28.7K
Empathy
10.1K
Some researchers suggest that altruism operates on empathy. Empathy is the capacity to understand another person’s perspective, to feel what he or she feels. An empathetic person makes an emotional connection with others and feels compelled to help (Batson, 1991). Empathy can be expressed in several ways, including cognitive, affective, and motor.
10.1K

