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Updated: Jan 21, 2026

Synthesis and Characterization of Supramolecular Colloids
Published on: April 22, 2016
Supramolecular photochemistry of encapsulated caged ortho-nitrobenzyl triggers
Nareshbabu Kamatham1, A Mohan Raj, Richard S Givens
1Department of Chemistry, University of Miami, Coral Gables, FL 33146, USA. murthy1@miami.edu.
Abstract:
ortho-Nitrobenzyl (oNB) triggers have been extensively used to release various molecules of interest. However, the toxicity and reactivity of the spent chromophore, o-nitrosobenzaldehyde, remains an unaddressed difficulty. In this study we have applied the well-established supramolecular photochemical concepts to retain the spent trigger o-nitrosobenzaldehyde within the organic capsule after release of water-soluble acids and alcohols. The sequestering power of organic capsules for spent chromophores during photorelease from ortho-nitrobenzyl esters, ethers and alcohols is demonstrated with several examples.
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