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Prevention of non-specific bronchial hyperreactivity. Dose-dependent effect of sodium cromoglycate metered dose
D Del Bufalo1, L Fasano, F Patalano
1Cattedra di Fisiopatologia Respiratoria, Universita Degli Studi Di Bologna, Italy.
Allergologia Et Immunopathologia
|March 1, 1988
Abstract:
The protective effect of different doses of sodium cromoglycate (4 mg, 12 mg and 20 mg) given as pressurized aerosol on fog-induced bronchoconstriction were investigated in three different groups of asthmatic patients. Premedication with the active drug was compared versus absence of premedication. The authors discuss their results by a statistical analysis of the FEV1 variations. Sodium cromoglycate effectively prevents fog-induced bronchoconstriction with a clear dose-dependent effect.