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Mastoiditis with Streptococcus pneumoniae serotype 19A in one-dose PCV13 vaccinated three-month-old infant

B Gülhan1, S Kanik-Yuksek1, A Ozkaya-Parlakay1

  • 1Department of Pediatric Infectious Diseases, University of Health Sciences, Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital, Ankara, Turkey.

Human Vaccines & Immunotherapeutics
|July 27, 2019
PubMed

Insights

Pneumococcal conjugate vaccines (PCV) have reduced disease, but a rare case shows Streptococcus pneumoniae serotype 19A can still cause mastoiditis in infants after otitis media.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Vaccinology

Background:

  • Pneumococcal conjugate vaccines (PCV) significantly decrease pneumococcal disease in high-income nations.
  • Turkey's National Immunization Programme incorporated PCV7 in 2009 and PCV13 in 2011.

Observation:

  • A three-month-old infant presented with acute otitis media.
  • The infant subsequently developed mastoiditis.

Findings:

  • The mastoiditis was confirmed to be secondary to Streptococcus pneumoniae serotype 19A infection.
  • This case highlights a potential complication despite widespread PCV use.

Implications:

  • Even with PCV13, serotype 19A remains a potential pathogen for invasive pneumococcal disease.
  • This underscores the importance of continued surveillance and potential updates to vaccination strategies.

Keywords:
Serotype 19Aacute otitis mediamastoiditispneumococcal conjugate vaccine

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