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Peripheral lymphocyte depletion in gold sodium thiomalate-treated rheumatoid arthritis patients
M S Lundberg1, G W Cannon, J R Ward
1Division of Rheumatology, University of Utah Medical Center, Salt Lake City.
Arthritis and Rheumatism
|July 1, 1988
Abstract:
It has been reported that gold sodium thiomalate treatment of rheumatoid arthritis reduces the number of peripheral blood lymphocytes. In a prospective, double-blind, randomized trial comparing gold sodium thiomalate, auranofin, and placebo in the treatment of rheumatoid arthritis, we investigated absolute lymphocyte counts. We found that peripheral lymphocyte counts decreased, but there was no correlation with clinical change in disease activity.