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Exploring the Science behind Bifidobacterium breve M-16V in Infant Health

Chyn Boon Wong1, Noriyuki Iwabuchi2, Jin-Zhong Xiao3

  • 1Next Generation Science Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa 252-8583, Japan.

Nutrients
|July 28, 2019
PubMed

Insights

Bifidobacterium breve M-16V shows promise in preventing necrotizing enterocolitis (NEC) and allergies in infants. This probiotic may support gut health and immune balance, especially in premature infants.

Area of Science:

  • Microbiology
  • Pediatrics
  • Immunology

Background:

  • Probiotics are explored for infant health, but strain-specific benefits require clarification.
  • Bifidobacterium breve M-16V is a widely used probiotic in infants.
  • M-16V shows potential in preventing necrotizing enterocolitis (NEC) and allergic diseases.

Purpose of the Study:

  • To review the beneficial effects of Bifidobacterium breve M-16V in infants.
  • To explore its role in preventing premature birth complications and immune-mediated disorders.
  • To summarize evidence supporting M-16V for infant health, particularly in preterm infants.

Main Methods:

  • Literature review of studies on Bifidobacterium breve M-16V.
  • Analysis of mechanistic studies on M-16V's effects on gut microbiota and immune regulation.
  • Synthesis of findings related to NEC and allergy prevention in infants.

Main Results:

  • Bifidobacterium breve M-16V promotes early gut microbial colonization.
  • M-16V may regulate immune balance and inflammatory responses.
  • Evidence suggests M-16V can protect high-risk infants from NEC and allergies.

Conclusions:

  • Bifidobacterium breve M-16V demonstrates potential as a probiotic for infant health.
  • It may be particularly beneficial for vulnerable preterm infants.
  • M-16V offers a promising strategy for preventing NEC and allergies.

Keywords:
Bifidobacterium breve M-16Vclinical efficacygut microbiotainfant healthprobiotics

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