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High-voltage irradiation and combination chemotherapy for malignant pheochromocytoma
M Z Siddiqui1, F E Von Eyben, G Spanos
1Department of Oncology, Tawam Hospital, Al Ain, Abu Dhabi, United Arab Emirates.
Cancer
|August 15, 1988
Abstract:
A 29-year-old man with metastatic extraadrenal pheochromocytoma developed paraplegia which reversed completely after megavoltage irradiation of the dorsolumbar spine. Later, treated with cyclophosphamide, vincristine, and dacarbazine, he had a temporary decrease in plasma norepinephrine concentration, a partial recalcification of bone lesions, and a decrease in the need for antihypertensive treatment for 12 months. Irradiation and combination chemotherapy should be evaluated further in the management of malignant pheochromocytoma.