Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Clinical Trials01:16

Clinical Trials

10.2K
Clinical trials are prospective experimental studies conducted on humans to determine the safety and efficacy of treatments, drugs, diet methods, and medical devices. Using statistics in clinical trials enables researchers to derive reasonable and accurate conclusions from the collected data, allowing them to make wise decisions in uncertain situations. In medical research, statistical methods are crucial for preventing errors and bias.
There are four phases in a clinical trial. A phase one...
10.2K
Clinical Trials: Overview01:11

Clinical Trials: Overview

4.6K
Clinical development focuses on how the drug will interact with the human body and encompasses four key phases of clinical trials, each serving a specific purpose in assessing the safety and effectiveness of new drugs. These phases overlap and build upon one another. Phase I involves a small group of healthy volunteers (typically 20-80 individuals) or, in cases where significant toxicity is expected, patients with the targeted disease, such as cancer or AIDS. The volunteers are tested for...
4.6K
Statistical Software for Data Analysis and Clinical Trials01:12

Statistical Software for Data Analysis and Clinical Trials

1.4K
Statistical software is pivotal in data analysis and clinical trials by providing tools to analyze data, draw conclusions, and make predictions. These software packages range from simple data management applications to complex analytical platforms, supporting various statistical tests, models, and simulation techniques. Their significance lies in their ability to handle vast amounts of data with precision and efficiency, enabling researchers to validate hypotheses, identify trends, and make...
1.4K
Trial and Error and Algorithm01:12

Trial and Error and Algorithm

399
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
399
Phase Diagrams02:39

Phase Diagrams

49.0K
A phase diagram combines plots of pressure versus temperature for the liquid-gas, solid-liquid, and solid-gas phase-transition equilibria of a substance. These diagrams indicate the physical states that exist under specific conditions of pressure and temperature and also provide the pressure dependence of the phase-transition temperatures (melting points, sublimation points, boiling points). Regions or areas labeled solid, liquid, and gas represent single phases, while lines or curves represent...
49.0K
Phase Transitions02:31

Phase Transitions

22.7K
Whether solid, liquid, or gas, a substance's state depends on the order and arrangement of its particles (atoms, molecules, or ions). Particles in the solid pack closely together, generally in a pattern. The particles vibrate about their fixed positions but do not move or squeeze past their neighbors. In liquids, although the particles are closely spaced, they are randomly arranged. The position of the particles are not fixed—that is, they are free to move past their neighbors to...
22.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Variability of Preschool Stuttering During a Day.

American journal of speech-language pathology·2026
Same author

A Phase I Trial of iLidcombe: Online Treatment for Young Children Who Stutter.

American journal of speech-language pathology·2026
Same author

Development of a stand-alone eHealth treatment: iCamperdown.

Journal of fluency disorders·2025
Same author

Ancient <i>Borrelia</i> genomes document the evolutionary history of louse-borne relapsing fever.

Science (New York, N.Y.)·2025
Same author

Contemporary clinical conversations about stuttering: Does the cause of stuttering matter to clinicians?

International journal of speech-language pathology·2024
Same author

The Fifth Croatia Stuttering Symposium: Part II. Natural recovery from early stuttering.

Journal of fluency disorders·2023

Related Experiment Video

Updated: Jan 21, 2026

In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

2.2K

Three Lidcombe program clinic visit options: a phase II trial.

Sarita Koushik1, Sally Hewat1, Mark Onslow2

  • 1University of Newcastle, Newcastle, Australia.

Journal of Communication Disorders
|July 28, 2019
PubMed
Summary

Fortnightly clinic visits for the Lidcombe Program (LP) showed comparable stuttering outcomes to weekly visits at 9 months. This suggests less frequent visits may be effective for some families in stuttering treatment.

Keywords:
InterventionRandomized controlled trialService deliveryStuttering

More Related Videos

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
04:05

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis

Published on: June 30, 2023

2.8K
Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides
05:16

Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides

Published on: May 7, 2020

7.3K

Related Experiment Videos

Last Updated: Jan 21, 2026

In Silico Clinical Trials for Cardiovascular Disease
09:09

In Silico Clinical Trials for Cardiovascular Disease

Published on: May 27, 2022

2.2K
Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
04:05

Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis

Published on: June 30, 2023

2.8K
Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides
05:16

Characterizing Exon Skipping Efficiency in DMD Patient Samples in Clinical Trials of Antisense Oligonucleotides

Published on: May 7, 2020

7.3K

Area of Science:

  • Speech-language pathology
  • Pediatric audiology

Background:

  • The Lidcombe Program (LP) traditionally recommends weekly clinic visits.
  • This recommendation lacks empirical support and may not reflect current clinical practice.
  • Previous research indicates variability in LP service delivery models.

Purpose of the Study:

  • To compare the efficacy of different clinic visit frequencies within the Lidcombe Program.
  • To investigate alternative service delivery models for stuttering treatment.

Main Methods:

  • A randomized controlled trial involving 31 children with stuttering.
  • Comparison of three service delivery models: twice-weekly, weekly, and fortnightly clinic visits.
  • Treatment followed manualised Lidcombe Program procedures with outcome measures of percentage syllables stuttered.

Main Results:

  • Twice-weekly and fortnightly formats were not universally suitable for all families.
  • Fortnightly clinic visits demonstrated comparable stuttering outcomes to weekly visits at 9 months post-randomization.
  • No significant difference in efficacy was found between weekly and fortnightly schedules at the 9-month mark.

Conclusions:

  • The findings support further large-scale trials comparing weekly versus less frequent Lidcombe Program clinic visits.
  • Less frequent clinic visit schedules may be a viable option for stuttering management.
  • This research challenges traditional assumptions about visit frequency in stuttering therapy.