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Updated: Jan 21, 2026

Orthotopic Left Lung Transplantation in Rats
Published on: July 3, 2025
Lung Transplant for the Critical Care Nurse
Kevin C Carney1, Tanya Bronzell-Wynder1, Karen Gronek2
1Lung Center Service Line, Temple University Hospital, 6th floor Rock Pavilion, 3401 North Broad Street, Philadelphia, PA 19140, USA.
Abstract:
Lung transplantation is an established treatment of select patients with end-stage pulmonary disease. Lung transplantation should be considered for patients with end-stage pulmonary disease who have an expected 2-year survival of less than 50% without lung transplant and an expected 5-year survival of greater than 80% after transplant. This article reviews routine postsurgical intensive care unit management, along with management of complications such as acute kidney injury, atrial arrhythmias, deep vein thrombosis, primary graft dysfunction, hyperammonemia syndrome, and thrombocytopenia. Finally, management of long-term issues, including diabetes mellitus, hypertension, and bronchial stenosis, is discussed.
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Critical Region, Critical Values and Significance Level
In hypothesis testing, a sample statistic is converted to a test statistic using z, t, or chi-square distribution. A critical region is an area under the curve in probability distributions demarcated by the critical value. When the test statistic falls in this region, it suggests that the null hypothesis must be rejected. As this region contains all those values of the...
Critical Values