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Updated: Jan 21, 2026

Assessing the Coherence of Parents' Short Narratives Regarding their Child Using the Five-Minute Speech Sample Procedure
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Posterior Reversible Encephalopathy Syndrome in a Five-Year-Old Child: A Case Report

Sencan Acar1, Mustafa Emre Kavlak2, Baris Demir3

  • 1Department of Gastroenterology and Organ Transplant Center, Sakarya University School of Medicine, Sakarya, Turkey.

Transplantation Proceedings
|July 29, 2019
PubMed

Insights

Posterior reversible encephalopathy syndrome (PRES) is a rare neurological condition. This case highlights PRES developing in a pediatric liver transplant patient after a blood transfusion and tacrolimus therapy.

Area of Science:

  • Neurology
  • Pediatric Medicine
  • Transplantation

Background:

  • Posterior reversible encephalopathy syndrome (PRES) is a neuroradiologic finding with unclear etiology.
  • PRES is associated with various factors, including immunosuppressive therapy and recent transfusions.

Observation:

  • A 5½-year-old boy developed PRES on the sixth day post-living donor liver transplantation.
  • The patient was receiving tacrolimus therapy and had undergone a red blood cell transfusion 6 hours prior to PRES onset.

Findings:

  • This case presents a potential link between tacrolimus, blood transfusion, and PRES in a pediatric liver transplant recipient.
  • The temporal association suggests these factors may contribute to PRES development.

Implications:

  • PRES should be considered in pediatric transplant patients presenting with acute neurological symptoms.
  • Awareness of this association can aid in early diagnosis and management of PRES in immunocompromised populations.

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