Related Experiment Video

Updated: Jan 21, 2026

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
05:02

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

33.6K

MMRdb: Measles, mumps, and rubella viruses database and analysis resource

Iman Almansour1, Mazen Alhagri2

  • 1Epidemic Diseases Department, Institute for Research and Medical Consultations, Imam Abdulrahman Bin Faisal University, Dammam 31441, Saudi Arabia.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases
|July 29, 2019
PubMed

Insights

Measles, mumps, and rubella viruses (MMR) can cause illness despite vaccination. A new database, MMRdb, tracks genetic and antigenic variations to aid in developing better diagnostics and vaccines.

Area of Science:

  • Virology
  • Immunology
  • Bioinformatics

Background:

  • Measles, mumps, and rubella viruses are significant human pathogens.
  • Outbreaks occur even in highly vaccinated populations, highlighting the need for continuous monitoring.
  • Existing resources may not adequately address the genetic and antigenic variations of these viruses.

Purpose of the Study:

  • To introduce MMRdb, a centralized web database and analysis resource for measles, mumps, and rubella viruses.
  • To provide researchers with tools to monitor viral genetic and antigenic diversity.
  • To facilitate the development of improved diagnostics, vaccines, and immunotherapeutics.

Main Methods:

  • Development of a user-friendly web database (MMRdb).
  • Integration of search functionalities for viral sequence information (gene level, geographic location, year, host).
  • Inclusion of experimentally verified B cell and T cell antigenic epitopes.
  • Implementation of computational tools: multiple sequence alignment, Geo Chart, and BLAST search.

Main Results:

  • MMRdb provides comprehensive sequence data for measles, mumps, and rubella viruses.
  • The database includes experimentally validated antigenic epitopes.
  • Integrated bioinformatics tools enable detailed sequence analysis and comparison.

Conclusions:

  • MMRdb serves as a valuable resource for tracking genetic and antigenic variations of MMR viruses.
  • The database supports monitoring viral geographic spread and evolution.
  • MMRdb will aid researchers in developing next-generation diagnostics and vaccines against measles, mumps, and rubella.
Keywords:
DatabaseMMRMeaslesMumpsRubella

More Related Videos

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases07:41

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Published on: May 17, 2019

9.5K
Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 112:00

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

10.7K

Related Concept Videos

Short-distance Transport of Resources02:12

Short-distance Transport of Resources

Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.
17.5K
What are Viruses?00:50

What are Viruses?

Overview
127.8K
Xylem and Transpiration-driven Transport of Resources02:03

Xylem and Transpiration-driven Transport of Resources

The xylem of vascular plants distributes water and dissolved minerals that are taken up by the roots to the rest of the plant. The cells that transport xylem sap are dead upon maturity, and the movement of xylem sap is a passive process.
26.4K
Introduction to Virus01:28

Introduction to Virus

Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
1.3K
Viruses of Archaea01:29

Viruses of Archaea

Archaeal viruses play a crucial role in the ecosystems of extremophilic archaea, particularly those belonging to the phyla Euryarchaeota and Crenarchaeota. By shaping host evolution and facilitating gene transfer, these viruses influence microbial communities and contribute to genetic diversity in extreme environments. The archaea they infect thrive in acidic hot springs and hydrothermal vents characterized by high temperatures and low pH. Archaeal viruses exhibit remarkable structural...
473
Viruses with RNA Genomes01:29

Viruses with RNA Genomes

RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
853