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Isolated growth hormone deficiency presenting with recurrent hypoglycaemia in a toddler

Hiya Boro1, Alpesh Goyal2, Rajesh Khadgawat2

  • 1Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India.

BMJ Case Reports
|July 29, 2019
PubMed

Insights

Growth hormone deficiency (GHD) is a rare cause of recurrent hypoglycemia in children. This case highlights the importance of thorough metabolic and hormonal evaluation for diagnosing childhood hypoglycemia.

Area of Science:

  • Pediatric Endocrinology
  • Metabolic Disorders
  • Hormone Deficiencies

Background:

  • Hypoglycemia in infants and children stems from various endocrine and metabolic issues.
  • Growth hormone deficiency (GHD) is an infrequently identified cause of recurrent fasting hypoglycemia.

Observation:

  • An 18-month-old boy experienced neuroglycopenic symptoms due to recurrent fasting hypoglycemia.
  • Laboratory results indicated ketotic hypoinsulinaemic hypoglycemia.

Findings:

  • The child was diagnosed with GHD after two failed stimulation tests.
  • Extensive metabolic and hormonal work-ups excluded other causes of hypoglycemia.

Implications:

  • This case underscores the rarity of GHD as a cause of pediatric hypoglycemia.
  • Emphasizes the necessity of comprehensive metabolic and hormonal assessments for diagnosing hypoglycemia in children.

Keywords:
endocrine systemmetabolic disorderspaediatrics (drugs and medicines)pituitary disorders

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